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ISO Recombinant Protein Service Rice Endosperm Specific Expression Platform

Categories Recombinant Protein Service
Brand Name: Oryzogen
Model Number: HY-ORYZ
Certification: ISO 9001
Place of Origin: China
MOQ: Negotiation
Price: Negotiation
Payment Terms: T/T
Supply Ability: Negotiation
Delivery Time: Negotiation
Packaging Details: Negotiation
Usage: Biological research, Biopharma
Advantages: Animal component, high expression level, more biological safety
Bioreactor: Rice endosperm specific expression platform
Formulation: Lyophilized powder or solution
Purity: Greater than 90%
Production Type: Technical services for recombinant protein
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    ISO Recombinant Protein Service Rice Endosperm Specific Expression Platform

    ISO Recombinant Protein Service Rice Endosperm Specific Expression Platform​


    Pilot Service


    Service ItemService Approach
    1. Purification workshop: 1500 square meters of existing pilot purification workshop, contains a grade D, C grade B + grade a clean area, meet with liquid, extraction, clarification and filtration, chromatography, concentrated and freeze-dried packing the whole process of production and test conditions.
    2. Process tank system: process tank and batching system for 50-2000L scale.
    3. Extraction platform:0.5-2.0 tons of extraction tank and filtration clarification sterilization unit, can realize the mixing, blending, heating extraction, cooling, material is set to deliver the liquid extraction process.
    4. GE(800) chromatography column, BPG(100mm, 300mm, 200mm), two sets of Chromaflow 150 column and 1sets of chromatography column, as well as a supporting column, UV detection and mapping system.
    5. Ultrafiltration system: Millipore ultrafitration system, with 10KD, 30KD and 300KD ultrafiltration membrane package, can achieve the 0-500L scale of the material liquid concentration, dialysis and other ultrafiltion process.
    6. Aseptic filling and freeze drying: two sets of B+ a grade a clean area freeze dry machine (0.5 cubic meters), the single batch of frozen dry capacity to reach 4-5Kg protein, can realize aseptic ingredients, filling, aseptic freeze-drying and other biological agents development process.
    1. Provide equipment and clean environment for customers to develop projects independently.
    2. Provide facilities and clean environment. Technical instruction and operation personnel to help customers develop pilot and production projects.
    3. Provide equipment leasing services, such as column, chromatography, ultrafiltration,ect..

    Common Equipment

    Lyophilization Unit


    The lyophilization unit, in the Class 100 clean area, is composed of two sets of lyophilizer, aseptic transferring window, hot and damp heat sterilization cabinet and manual packing machine etc. The products are prepared and packed in the sterile area after lyophilization. The production capacity reached 4-5kg lyophilization powder per batch.


    Ultrafiltration Unit

    The ultrafiltration unit is composed of ultrafiltration system and peristaltic pumps in Class C+A clean area. The Millipore manual ultrafiltration fixture, which can be installed with 2.5-5.0 square meter membrane, can be applied to various sizes of membrane pore size and ultrafiltration system. The ultrafiltration system is in the Class A clean area, which provides a good security for aseptic operation.

    Chromatographic Purification Unit

    The chromatographic purification unit, in the Class C clean area in accordance with GMP, is composed of 50~1000L buffer solution tanks, chromaflow 800 columns, peristaltic pumps, industrial grade UV detectors, spectrum acquisition systems and so on. The system also can match with other chromatography columns diameter from 100-800mm, such as BPG series (GE Healthcare), VERSA 450 and so on. The column packing and unpacking is performed by automatical Master Customer Asm (GE Healthcare), also matched a series of chromatography resins, such as ion exchange chromatography, hydrophobic chromatography and so on.

    Extraction Unit

    The extraction unit, in the Class D clean area, is composed of 2 sets of 1000L buffer preparation tanks, 3 sets of 1000L extracting tanks, pipeline system, sanitary centrifugal pump, frame filter press and cartridge filter. The buffer preparation tank can actualize buffer automatic mixing, heating and cooling, feed fluid transportation.The frame filter press is equipped with 50~300um aperture, and microporous filter, in 5 or 10 inch, can be matched with 0.22um, 0.45um and 1um filter element and so on.All tanks are washed by pure water and injection water spraying, and sterilized by pure steam.

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